Pesquisa | BVS IEC

1.

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke.

Alim, Ishraq; Caulfield, Joseph T; Chen, Yingxin; Swarup, Vivek; Geschwind, Daniel H; Ivanova, Elena; Seravalli, Javier; Ai, Youxi; Sansing, Lauren H; Ste Marie, Emma J; Hondal, Robert J; Mukherjee, Sushmita; Cave, John W; Sagdullaev, Botir T; Karuppagounder, Saravanan S; Ratan, Rajiv R.

Cell ; 177(5): 1262-1279.e25, 2019 05 16.

Artigo em Inglês | MEDLINE | ID: mdl-31056284

2.

Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke.

Shi, Ligen; Sun, Zeyu; Su, Wei; Xu, Fei; Xie, Di; Zhang, Qingxiu; Dai, Xuejiao; Iyer, Kartik; Hitchens, T Kevin; Foley, Lesley M; Li, Sicheng; Stolz, Donna B; Chen, Kong; Ding, Ying; Thomson, Angus W; Leak, Rehana K; Chen, Jun; Hu, Xiaoming.

Immunity ; 54(7): 1527-1542.e8, 2021 07 13.

Artigo em Inglês | MEDLINE | ID: mdl-34015256

3.

Neuroimmune mechanisms and therapies mediating post-ischaemic brain injury and repair.

Shichita, Takashi; Ooboshi, Hiroaki; Yoshimura, Akihiko.

Nat Rev Neurosci ; 24(5): 299-312, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-36973481

4.

Stroke genetics informs drug discovery and risk prediction across ancestries.

Mishra, Aniket; Malik, Rainer; Hachiya, Tsuyoshi; Jürgenson, Tuuli; Namba, Shinichi; Posner, Daniel C; Kamanu, Frederick K; Koido, Masaru; Le Grand, Quentin; Shi, Mingyang; He, Yunye; Georgakis, Marios K; Caro, Ilana; Krebs, Kristi; Liaw, Yi-Ching; Vaura, Felix C; Lin, Kuang; Winsvold, Bendik Slagsvold; Srinivasasainagendra, Vinodh; Parodi, Livia; Bae, Hee-Joon; Chauhan, Ganesh; Chong, Michael R; Tomppo, Liisa; Akinyemi, Rufus; Roshchupkin, Gennady V; Habib, Naomi; Jee, Yon Ho; Thomassen, Jesper Qvist; Abedi, Vida; Cárcel-Márquez, Jara; Nygaard, Marianne; Leonard, Hampton L; Yang, Chaojie; Yonova-Doing, Ekaterina; Knol, Maria J; Lewis, Adam J; Judy, Renae L; Ago, Tetsuro; Amouyel, Philippe; Armstrong, Nicole D; Bakker, Mark K; Bartz, Traci M; Bennett, David A; Bis, Joshua C; Bordes, Constance; Børte, Sigrid; Cain, Anael; Ridker, Paul M; Cho, Kelly.

Nature ; 611(7934): 115-123, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-36180795

5.

Tenecteplase for Stroke at 4.5 to 24 Hours with Perfusion-Imaging Selection.

Albers, Gregory W; Jumaa, Mouhammad; Purdon, Barbara; Zaidi, Syed F; Streib, Christopher; Shuaib, Ashfaq; Sangha, Navdeep; Kim, Minjee; Froehler, Michael T; Schwartz, Neil E; Clark, Wayne M; Kircher, Charles E; Yang, Ming; Massaro, Lori; Lu, Xiao-Yu; Rippon, Gregory A; Broderick, Joseph P; Butcher, Ken; Lansberg, Maarten G; Liebeskind, David S; Nouh, Amre; Schwamm, Lee H; Campbell, Bruce C V.

N Engl J Med ; 390(8): 701-711, 2024 Feb 22.

Artigo em Inglês | MEDLINE | ID: mdl-38329148

6.

p53 opens the mitochondrial permeability transition pore to trigger necrosis.

Vaseva, Angelina V; Marchenko, Natalie D; Ji, Kyungmin; Tsirka, Stella E; Holzmann, Sonja; Moll, Ute M.

Cell ; 149(7): 1536-48, 2012 Jun 22.

Artigo em Inglês | MEDLINE | ID: mdl-22726440

7.

Trial of Endovascular Thrombectomy for Large Ischemic Strokes.

Sarraj, Amrou; Hassan, Ameer E; Abraham, Michael G; Ortega-Gutierrez, Santiago; Kasner, Scott E; Hussain, M Shazam; Chen, Michael; Blackburn, Spiros; Sitton, Clark W; Churilov, Leonid; Sundararajan, Sophia; Hu, Yin C; Herial, Nabeel A; Jabbour, Pascal; Gibson, Daniel; Wallace, Adam N; Arenillas, Juan F; Tsai, Jenny P; Budzik, Ronald F; Hicks, William J; Kozak, Osman; Yan, Bernard; Cordato, Dennis J; Manning, Nathan W; Parsons, Mark W; Hanel, Ricardo A; Aghaebrahim, Amin N; Wu, Teddy Y; Cardona-Portela, Pere; Pérez de la Ossa, Natalia; Schaafsma, Joanna D; Blasco, Jordi; Sangha, Navdeep; Warach, Steven; Gandhi, Chirag D; Kleinig, Timothy J; Sahlein, Daniel; Elijovich, Lucas; Tekle, Wondwossen; Samaniego, Edgar A; Maali, Laith; Abdulrazzak, M Ammar; Psychogios, Marios N; Shuaib, Ashfaq; Pujara, Deep K; Shaker, Faris; Johns, Hannah; Sharma, Gagan; Yogendrakumar, Vignan; Ng, Felix C.

N Engl J Med ; 388(14): 1259-1271, 2023 Apr 06.

Artigo em Inglês | MEDLINE | ID: mdl-36762865

8.

Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct.

Huo, Xiaochuan; Ma, Gaoting; Tong, Xu; Zhang, Xuelei; Pan, Yuesong; Nguyen, Thanh N; Yuan, Guangxiong; Han, Hongxing; Chen, Wenhuo; Wei, Ming; Zhang, Jiangang; Zhou, Zhiming; Yao, Xiaoxi; Wang, Guoqing; Song, Weigen; Cai, Xueli; Nan, Guangxian; Li, Di; Wang, A Yi-Chou; Ling, Wentong; Cai, Chuwei; Wen, Changming; Wang, En; Zhang, Liyong; Jiang, Changchun; Liu, Yajie; Liao, Geng; Chen, Xiaohui; Li, Tianxiao; Liu, Shudong; Li, Jinglun; Gao, Feng; Ma, Ning; Mo, Dapeng; Song, Ligang; Sun, Xuan; Li, Xiaoqing; Deng, Yiming; Luo, Gang; Lv, Ming; He, Hongwei; Liu, Aihua; Zhang, Jingbo; Mu, Shiqing; Liu, Lian; Jing, Jing; Nie, Ximing; Ding, Zeyu; Du, Wanliang; Zhao, Xingquan.

N Engl J Med ; 388(14): 1272-1283, 2023 Apr 06.

Artigo em Inglês | MEDLINE | ID: mdl-36762852

9.

Tirofiban for Stroke without Large or Medium-Sized Vessel Occlusion.

Zi, Wenjie; Song, Jiaxing; Kong, Weilin; Huang, Jiacheng; Guo, Changwei; He, Wencheng; Yu, Yinquan; Zhang, Bo; Geng, Wanjie; Tan, Xiaolin; Tian, Yaoyu; Liu, Zongtao; Cao, Minghua; Cheng, Daoyou; Li, Bo; Huang, Wenguo; Liu, Junsheng; Wang, Pengfei; Yu, Zhou; Liang, Hao; Yang, Shuang; Tang, Mingshan; Liu, Wenhua; Huang, Xianjun; Liu, Shugai; Tang, Yufeng; Wu, Youlin; Yao, Li; Shi, Zhu; He, Pengcheng; Zhao, Haojin; Chen, Zhuo; Luo, Jun; Wan, Yue; Shi, Qiang; Wang, Maorong; Yang, De; Chen, Xianglin; Huang, Fang; Mu, Jinlin; Li, Hao; Li, Zhimin; Zheng, Jingbang; Xie, Shunli; Cai, Tieying; Peng, Yuqi; Xie, Weihua; Qiu, Zhongming; Liu, Chang; Yue, Chengsong.

N Engl J Med ; 388(22): 2025-2036, 2023 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-37256974

10.

Brain vulnerability and viability after ischaemia.

Daniele, Stefano G; Trummer, Georg; Hossmann, Konstantin A; Vrselja, Zvonimir; Benk, Christoph; Gobeske, Kevin T; Damjanovic, Domagoj; Andrijevic, David; Pooth, Jan-Steffen; Dellal, David; Beyersdorf, Friedhelm; Sestan, Nenad.

Nat Rev Neurosci ; 22(9): 553-572, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34290397

11.

Brain Ischemia Suppresses Immunity in the Periphery and Brain via Different Neurogenic Innervations.

Liu, Qiang; Jin, Wei-Na; Liu, Yaou; Shi, Kaibin; Sun, Haoran; Zhang, Fang; Zhang, Chao; Gonzales, Rayna J; Sheth, Kevin N; La Cava, Antonio; Shi, Fu-Dong.

Immunity ; 46(3): 474-487, 2017 03 21.

Artigo em Inglês | MEDLINE | ID: mdl-28314594

12.

LOX-1 and MMP-9 Inhibition Attenuates the Detrimental Effects of Delayed rt-PA Therapy and Improves Outcomes After Acute Ischemic Stroke.

Arkelius, Kajsa; Wendt, Trevor S; Andersson, Henrik; Arnou, Anaële; Gottschalk, Michael; Gonzales, Rayna J; Ansar, Saema.

Circ Res ; 134(8): 954-969, 2024 Apr 12.

Artigo em Inglês | MEDLINE | ID: mdl-38501247

13.

Potential circadian effects on translational failure for neuroprotection.

Esposito, Elga; Li, Wenlu; T Mandeville, Emiri; Park, Ji-Hyun; Sencan, Ikbal; Guo, Shuzhen; Shi, Jingfei; Lan, Jing; Lee, Janice; Hayakawa, Kazuhide; Sakadzic, Sava; Ji, Xunming; Lo, Eng H.

Nature ; 582(7812): 395-398, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32494010

14.

Interpericyte tunnelling nanotubes regulate neurovascular coupling.

Alarcon-Martinez, Luis; Villafranca-Baughman, Deborah; Quintero, Heberto; Kacerovsky, J Benjamin; Dotigny, Florence; Murai, Keith K; Prat, Alexandre; Drapeau, Pierre; Di Polo, Adriana.

Nature ; 585(7823): 91-95, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32788726

15.

Direct neuronal conversion of microglia/macrophages reinstates neurological function after stroke.

Irie, Takashi; Matsuda, Taito; Hayashi, Yoshinori; Matsuda-Ito, Kanae; Kamiya, Akihide; Masuda, Takahiro; Prinz, Marco; Isobe, Noriko; Kira, Jun-Ichi; Nakashima, Kinichi.

Proc Natl Acad Sci U S A ; 120(42): e2307972120, 2023 10 17.

Artigo em Inglês | MEDLINE | ID: mdl-37812721

16.

Endovascular thrombectomy plus medical care versus medical care alone for large ischaemic stroke: 1-year outcomes of the SELECT2 trial.

Sarraj, Amrou; Abraham, Michael G; Hassan, Ameer E; Blackburn, Spiros; Kasner, Scott E; Ortega-Gutierrez, Santiago; Hussain, Muhammad Shazam; Chen, Michael; Johns, Hannah; Churilov, Leonid; Pujara, Deep K; Shaker, Faris; Maali, Laith; Cardona Portela, Pere; Herial, Nabeel A; Gibson, Daniel; Kozak, Osman; Arenillas, Juan F; Yan, Bernard; Pérez de la Ossa, Natalia; Sundararajan, Sophia; Hu, Yin C; Cordato, Dennis J; Manning, Nathan W; Hanel, Ricardo A; Aghaebrahim, Amin N; Budzik, Ronald F; Hicks, William J; Blasco, Jordi; Wu, Teddy Y; Tsai, Jenny P; Schaafsma, Joanna D; Gandhi, Chirag D; Al-Mufti, Fawaz; Sangha, Navdeep; Warach, Steven; Kleinig, Timothy J; Yogendrakumar, Vignan; Ng, Felix; Samaniego, Edgar A; Abdulrazzak, Mohammad A; Parsons, Mark W; Rahbar, Mohammad H; Nguyen, Thanh N; Fifi, Johanna T; Mendes Pereira, Vitor; Lansberg, Maarten G; Albers, Greg W; Furlan, Anthony J; Jabbour, Pascal.

Lancet ; 403(10428): 731-740, 2024 Feb 24.

Artigo em Inglês | MEDLINE | ID: mdl-38346442

17.

Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion.

Jovin, Tudor G; Li, Chuanhui; Wu, Longfei; Wu, Chuanjie; Chen, Jian; Jiang, Changchun; Shi, Zhonghua; Gao, Zongen; Song, Cunfeng; Chen, Wenhuo; Peng, Ya; Yao, Chen; Wei, Ming; Li, Tong; Wei, Liping; Xiao, Guodong; Yang, Hua; Ren, Ming; Duan, Jiangang; Liu, Xinfeng; Yang, Qingwu; Liu, Yuxiu; Zhu, Qingfeng; Shi, Wanchao; Zhu, Qiyi; Li, Xiaobo; Guo, Zaiyu; Yang, Qi; Hou, Chengbei; Zhao, Wenbo; Ma, Qingfeng; Zhang, Yunzhou; Jiao, Liqun; Zhang, Hongqi; Liebeskind, David S; Liang, Hui; Jadhav, Ashutosh P; Wen, Changming; Brown, Scott; Zhu, Liangfu; Ye, Huawei; Ribo, Marc; Chang, Mingze; Song, Haiqing; Chen, Jun; Ji, Xunming.

N Engl J Med ; 387(15): 1373-1384, 2022 10 13.

Artigo em Inglês | MEDLINE | ID: mdl-36239645

18.

Trial of Endovascular Treatment of Acute Basilar-Artery Occlusion.

Tao, Chunrong; Nogueira, Raul G; Zhu, Yuyou; Sun, Jun; Han, Hongxing; Yuan, Guangxiong; Wen, Changming; Zhou, Peiyang; Chen, Wenhuo; Zeng, Guoyong; Li, Yuwen; Ma, Zhengfei; Yu, Chuanqing; Su, Junfeng; Zhou, Zhiming; Chen, Zhongjun; Liao, Geng; Sun, Yaxuan; Ren, Youquan; Zhang, Hui; Chen, Jie; Yue, Xincan; Xiao, Guodong; Wang, Li; Liu, Rui; Liu, Wenhua; Liu, Yong; Wang, Li; Zhang, Chao; Liu, Tianlong; Song, Jianlong; Li, Rui; Xu, Pengfei; Yin, Yamei; Wang, Guoping; Baxter, Blaise; Qureshi, Adnan I; Liu, Xinfeng; Hu, Wei.

N Engl J Med ; 387(15): 1361-1372, 2022 10 13.

Artigo em Inglês | MEDLINE | ID: mdl-36239644

19.

Endovascular Therapy for Acute Stroke with a Large Ischemic Region.

Yoshimura, Shinichi; Sakai, Nobuyuki; Yamagami, Hiroshi; Uchida, Kazutaka; Beppu, Mikiya; Toyoda, Kazunori; Matsumaru, Yuji; Matsumoto, Yasushi; Kimura, Kazumi; Takeuchi, Masataka; Yazawa, Yukako; Kimura, Naoto; Shigeta, Keigo; Imamura, Hirotoshi; Suzuki, Ichiro; Enomoto, Yukiko; Tokunaga, So; Morita, Kenichi; Sakakibara, Fumihiro; Kinjo, Norito; Saito, Takuya; Ishikura, Reiichi; Inoue, Manabu; Morimoto, Takeshi.

N Engl J Med ; 386(14): 1303-1313, 2022 04 07.

Artigo em Inglês | MEDLINE | ID: mdl-35138767

20.

Association of the Timing of Atrial Fibrillation Detection and Insular Involvement With the Risk of Embolic Events After Acute Ischemic Stroke.

Tokunaga, Keisuke; Toyoda, Kazunori; Kimura, Shunsuke; Minematsu, Kazuo; Yasaka, Masahiro; Okada, Yasushi; Yoshimura, Sohei; Koga, Masatoshi.

Ann Neurol ; 95(2): 338-346, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-37807081

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